DIOCTADECYLAMINE
Synonym(s):Distearylamine;DODA
- CAS NO.：112-99-2
- Empirical Formula: C36H75N
- Molecular Weight: 521.99
- MDL number: MFCD00048494
- EINECS: 204-020-2
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-01-13 11:24:38
What is DIOCTADECYLAMINE?
The Uses of DIOCTADECYLAMINE
Dioctadecylamine (DODA) is suitable reagent used in the synthesis of the following:
- Dioctadecylamine-BCN (bicyclo[6.1.0]nonyne) conjugate.
- Lipid derivatives of bisethylnorspermine (BSP).
- Functional VP (N-vinylpyrrolidone ) polymers.
- As a reactant in the synthesis of 4,4′-azobis(4-cyano-N,N-dioctadecyl)pentanamide (DODA-501) by reacting with disuccinimidyl 4,4′-azobis(4-cyanovalerate).
- As a reagent in the synthesis of dioctadecyl heptapeptides.
- As a phase transfer and stabilizer agent for gold nanoparticles (AuNPs) in non-polar solvent.
General Description
Dioctadecylamine (DODA), a secondary amine, is a fatty amine derivative. Its biodegradation potential has been assessed. It has been observed that in aqueous medium DODA self organizes into plate like structures. Its partial charge distribution as a function of its conformation has been analyzed. The phase diagram of dioctadecylamine Langmuir monolayers has been determined and investigations show it does not form a monolayer above pH 3.9. DODA has been utilized in forming liposomes, cationic lipids or lipid chelating agents.
Properties of DIOCTADECYLAMINE
| Melting point: | 71-73 °C |
| Boiling point: | 524.75°C (estimate) |
| Density | 0.9086 (estimate) |
| refractive index | 1.4841 (estimate) |
| solubility | water: soluble(lit.) |
| pka | 10.84±0.19(Predicted) |
| BRN | 1801688 |
| EPA Substance Registry System | 1-Octadecanamine, N-octadecyl- (112-99-2) |
Safety information for DIOCTADECYLAMINE
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for DIOCTADECYLAMINE
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