Dimethylaminopropionitrile

Chemical properties

clear colorless liquid

The Uses of Dimethylaminopropionitrile

3- Dimethylaminopropionitrile is used as a solvent, dielectric fluid, and an intermediate.

The Uses of Dimethylaminopropionitrile

3-(Dimethylamino)propionitrile has been used:

• to initiate the organic polymerization during the synthesis of class I hybrid poly(N-isopropylacrylamide)/silica hydrogels
• in preparation of cysteine modifying agents based on the solvatochromic fluorophore 4-N,N-dimethylamino-1,8-naphthalimide (4-DMN)

Production Methods

3-Dimethylaminopropionitrile is derived from heating barium ethyl sulfate and KCN with subsequent distillation.

General Description

Colorless liquid. Mp: -44.3°C; bp: 171-172°C. Density 0.87 g cm-3 at 20°C). Water-soluble. Used in the manufacture of polyurethane foam. Excessive exposure leads to urologic and neurologic disorders.

Reactivity Profile

Dimethylaminopropionitrile is combustible but non-flammable (flash point > 140°F), reacts with oxidizing agents (Hazardous Chemicals Desk Reference, p. 426 (1987)). Reacts violently with LIAlH4, a strong reducing agent. Emits toxic oxides of nitrogen and cyanide fumes when heated to decomposition.

Safety Profile

Poison by intravenous route. Moderately toxic by ingestion and skin contact. A skin and eye irritant. Flammable liquid when exposed to heat, flame, or oxidizers; can react with oxidizing materials. To fight fire, use foam, CO2, dry chemical. When heated to decomposition it emits highly toxic fumes of NOx and CN-. See also NITRILES.