Diethyl N-[5-methylamino-2-thenoyl]-L-glutamate
- CAS NO.:112889-02-8
- Empirical Formula: C15H22N2O5S
- Molecular Weight: 342.41
- MDL number: MFCD09750956
- SAFETY DATA SHEET (SDS)
- Update Date: 2025-07-16 09:54:04
What is Diethyl N-[5-methylamino-2-thenoyl]-L-glutamate?
The Uses of Diethyl N-[5-methylamino-2-thenoyl]-L-glutamate
N-[[5-(Methylamino)-2-thienyl]carbonyl]-L-glutamic Acid Diethyl Ester can be used as reactant/reagent for synthetic preparation of Raltitrexed (anticancer agent). An intermediate or impurity in the synthesis of Raltitrexed (R100500). Raltitrexed (R100500) is folate-based inhibitor of thymidylate synthase; rapidly and extensively metabolized to its more potent polyglutamate derivatives. Antineoplastic.
Properties of Diethyl N-[5-methylamino-2-thenoyl]-L-glutamate
| Boiling point: | 519.6±50.0 °C(Predicted) |
| Density | 1.231 |
| storage temp. | under inert gas (nitrogen or Argon) at 2–8 °C |
| pka | 12.89±0.46(Predicted) |
Safety information for Diethyl N-[5-methylamino-2-thenoyl]-L-glutamate
Computed Descriptors for Diethyl N-[5-methylamino-2-thenoyl]-L-glutamate
New Products
4,4-Difluoropiperidine hydrochloride tert-butyl 9-methoxy-3-azaspiro[5.5]undecane-3-carboxylate Indole Methyl Resin N-Isopropylurea N,N-Dicyclohexylcarbodiimide(DCC) MELDRUMS ACID 5-METHYLISOXAZOLE-4-CARBOXYLIC ACID Magnessium Bis glycinate Zinc ascorbate 1-bromo-2-butyne 2-acetamidophenol 9(10H)-anthracenone Erythrosin B, 4-Piperidinopiperidine 2-((4-morpholinophenylamino) (methylthio) methylene) malononitrile 2,4-dihydroxybenzaldehyde 3-(4-morpholinophenylamino)-5-amino-1H-pyrazole-4-carbonitrile Methyl 2-methylquinoline-6-carboxylate 2,6-dichloro-4-nitropyridine 4-Bromo-2-chlorobenzonitrile 2-(benzylamino)acetic acid hydrochloride 4-(tert-Butoxycarbonylamino)but- 2-ynoic acid 3,4-dihydro-2H-benzo[b][1,4]dioxepine 1-Phenyl-1-cycloprppanecarboxylicacidRelated products of tetrahydrofuran








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