Diethyl N-[5-methylamino-2-thenoyl]-L-glutamate
- CAS NO.:112889-02-8
- Empirical Formula: C15H22N2O5S
- Molecular Weight: 342.41
- MDL number: MFCD09750956
- SAFETY DATA SHEET (SDS)
- Update Date: 2025-07-16 09:54:04
What is Diethyl N-[5-methylamino-2-thenoyl]-L-glutamate?
The Uses of Diethyl N-[5-methylamino-2-thenoyl]-L-glutamate
N-[[5-(Methylamino)-2-thienyl]carbonyl]-L-glutamic Acid Diethyl Ester can be used as reactant/reagent for synthetic preparation of Raltitrexed (anticancer agent). An intermediate or impurity in the synthesis of Raltitrexed (R100500). Raltitrexed (R100500) is folate-based inhibitor of thymidylate synthase; rapidly and extensively metabolized to its more potent polyglutamate derivatives. Antineoplastic.
Properties of Diethyl N-[5-methylamino-2-thenoyl]-L-glutamate
| Boiling point: | 519.6±50.0 °C(Predicted) |
| Density | 1.231 |
| storage temp. | under inert gas (nitrogen or Argon) at 2–8 °C |
| pka | 12.89±0.46(Predicted) |
Safety information for Diethyl N-[5-methylamino-2-thenoyl]-L-glutamate
Computed Descriptors for Diethyl N-[5-methylamino-2-thenoyl]-L-glutamate
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