Diethyl bis(hydroxymethyl)malonate
Synonym(s):Diethyl 2,2-bis(hydroxymethyl)malonate
- CAS NO.：20605-01-0
- Empirical Formula: C9H16O6
- Molecular Weight: 220.22
- MDL number: MFCD00009130
- EINECS: 243-916-8
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-01-13 11:17:30
What is Diethyl bis(hydroxymethyl)malonate?
Chemical properties
white to almost white crystalline solid
The Uses of Diethyl bis(hydroxymethyl)malonate
Diethyl bis(hydroxymethyl)malonate is used as a reagent for preparing 1,3-dioxanes from acetals, aldehydes and ketones. It is also used as an intermediate for the preparation of substituted malonic, acrylic and isobutyric esters, for conversion to the useful dienophiles, ?-bromomethylacrylic acid and its ethyl ester and to bis(bromomethyl)acetic acid and its methyl ester.
Properties of Diethyl bis(hydroxymethyl)malonate
| Melting point: | 49-51 °C (lit.) |
| Boiling point: | 281.15°C (rough estimate) |
| Density | 1.2286 (rough estimate) |
| refractive index | 1.4390 (estimate) |
| Flash point: | >230 °F |
| storage temp. | Sealed in dry,Room Temperature |
| pka | 12.59±0.10(Predicted) |
| form | Crystalline Solid |
| color | White to almost white |
| Water Solubility | Slightly soluble in water. |
| BRN | 1788515 |
| CAS DataBase Reference | 20605-01-0(CAS DataBase Reference) |
| NIST Chemistry Reference | Diethyl bis(hydroxymethyl)malonate(20605-01-0) |
| EPA Substance Registry System | Propanedioic acid, bis(hydroxymethyl)-, diethyl ester (20605-01-0) |
Safety information for Diethyl bis(hydroxymethyl)malonate
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation |
| Precautionary Statement Codes |
P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P332+P313:IF SKIN irritation occurs: Get medical advice/attention. P337+P313:IF eye irritation persists: Get medical advice/attention. |
Computed Descriptors for Diethyl bis(hydroxymethyl)malonate
New Products
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