DIETHYL (2-OXO-2-PHENYLETHYL)PHOSPHONATE
Synonym(s):Diethyl benzoylmethylphosphonate;Diethyl phenacylphosphonate;NSC 648426
- CAS NO.：3453-00-7
- Empirical Formula: C12H17O4P
- Molecular Weight: 256.23
- MDL number: MFCD00015342
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-01-13 11:13:25
What is DIETHYL (2-OXO-2-PHENYLETHYL)PHOSPHONATE?
The Uses of DIETHYL (2-OXO-2-PHENYLETHYL)PHOSPHONATE
Reactant involved in:
- Asymmetric Michael addition of β-oxo phosphonates to nitro olefins
- Gem-chlorofluorination of keto phosphonates with subsequent functionalization of the products
- Cyclocondensation reactions to produce arylphosphonates
- Diazo transfer reactions for synthesis of diazo-phosphonyl compounds
- Horner-Wadsworth-Emmons reactions
- Inverse-electron-demand Diels-Alder reactions
What are the applications of Application
Diethyl (2-oxo-2-phenylethyl)phosphonate is a versatile Wadsworth-Emmons Reagent
Synthesis Reference(s)
Synthetic Communications, 26, p. 2561, 1996 DOI: 10.1080/00397919608004568
Properties of DIETHYL (2-OXO-2-PHENYLETHYL)PHOSPHONATE
| Boiling point: | 192-193 °C/11 mmHg (lit.) |
| Density | 1.179 g/mL at 25 °C (lit.) |
| refractive index | n |
| Flash point: | >230 °F |
| form | clear liquid |
| color | White to Yellow to Green |
| CAS DataBase Reference | 3453-00-7 |
Safety information for DIETHYL (2-OXO-2-PHENYLETHYL)PHOSPHONATE
Computed Descriptors for DIETHYL (2-OXO-2-PHENYLETHYL)PHOSPHONATE
New Products
Mirtazapine Impurity C/Mirtazapine Lactam Impurity Cyclopropane-1,1-dicarboxylic acid [1]Benzothieno[2,3-c]pyridine, 1,7-dichloro-8-methyl- (S)-3-Fluoro-pyrrolidine hydrochloride Cyclobutylamine 1-Bromo-2-Methoxy-3-Nitrobenzene 3-Oxocyclobutane-1-carboxylicacid (4-Bromophenyl)(3,4-dimethoxyphenyl)methanone N-Nitroso hydroxy Cetrizine EP Impurity-A Noradrenaline EP Impurity D/Noradrenaline Methyl Ether Cetirizine EP Impurity A/Cetirizine CBHP Impurity Lantanoprost rc B Clidinium Bromide Impurity 2-chloro-7-cyclopentyl-N,N-dimethylpyrrolo [2,3-d]pyrimidine-6-carbox amide 4-amino-2-fluoro-N- methylbenzamide N-(2-chloropyrimidin-4-yl)-N,2,3- trimethyl-2H- indazol 6-amine 5-Chloro-3- Methyl -1,3-2-benzoxazol-2(3H)-one 4-Bromo-2-fluoro-N-methylbenzamide N-Boc-1,4-butanediamine 4-Dimethylamino pyridine 2-Chlorotrityl Chloride 4-Bromoaniline 5-Bromo-2-chlorobenzoic acid 1,2,3,9-Tetrahydro-4(H)-carbazol-4-oneRelated products of tetrahydrofuran
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