Diethyl (2-oxo-2-phenylethyl)phosphonate
Synonym(s):Diethyl benzoylmethylphosphonate;Diethyl phenacylphosphonate;NSC 648426
- CAS NO.：3453-00-7
- Empirical Formula: C12H17O4P
- Molecular Weight: 256.23
- MDL number: MFCD00015342
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-09-12 18:48:28
What is Diethyl (2-oxo-2-phenylethyl)phosphonate?
The Uses of Diethyl (2-oxo-2-phenylethyl)phosphonate
Reactant involved in:
- Asymmetric Michael addition of β-oxo phosphonates to nitro olefins
- Gem-chlorofluorination of keto phosphonates with subsequent functionalization of the products
- Cyclocondensation reactions to produce arylphosphonates
- Diazo transfer reactions for synthesis of diazo-phosphonyl compounds
- Horner-Wadsworth-Emmons reactions
- Inverse-electron-demand Diels-Alder reactions
What are the applications of Application
Diethyl (2-oxo-2-phenylethyl)phosphonate is a versatile Wadsworth-Emmons Reagent
Synthesis Reference(s)
Synthetic Communications, 26, p. 2561, 1996 DOI: 10.1080/00397919608004568
Properties of Diethyl (2-oxo-2-phenylethyl)phosphonate
| Boiling point: | 192-193 °C/11 mmHg (lit.) |
| Density | 1.179 g/mL at 25 °C (lit.) |
| refractive index | n |
| Flash point: | >230 °F |
| form | clear liquid |
| color | White to Yellow to Green |
| CAS DataBase Reference | 3453-00-7 |
Safety information for Diethyl (2-oxo-2-phenylethyl)phosphonate
Computed Descriptors for Diethyl (2-oxo-2-phenylethyl)phosphonate
New Products
5-bromo-4-fluoro-2-nitrobenzaldehyde (R)-(-)-2-Amino-1-propanol Cyclobutanone Fmoc-OSu 1-(2-Chloroethyl)pyrrolidine Hydrochloride 2-Amino-2-(4-methylphenyl)acetic acid β-Bromostyrene Ethyl 3-phenylpropanoate Phenethyl cinnamate Dipropyl disulfide 4 pentyn 1 ol N-Vinylformamide Methacrylate-PEG-Methacrylate, Mn:35000 2,4-Dihydroxyacetophenone 2-Chloro 5-Fluoro Pyridine Vasicinone 2-Chloroisonicotinic Acid Tween 80 or Polysorbate 80 2-Butyn-1-oL 2-Pentyn-1-oL 4-Nitrobenzotrifluoride N-(4-fluoro-2-methoxy-5-nitrophenyl)-4-(1-methyl-1H-indol-3-yl)pyrimidin-2-amine Pirtobrutinib intd. N-(4-Cyano-3-(trifluoromethyl)phenyl)-2-methyloxirane-2-carboxamideRelated products of tetrahydrofuran
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