DIDS

Chemical properties

yellow to yellow-green or brown powder

The Uses of DIDS

Stilbene disulfonates have been employed to inhibit anion transport in a large number of mammalian cell types (GABA, Cl-). Some stilbene disulfonates can bind specifically to proteins that are not anion transporters. DIDS reacts with CD4 glycoprotein on T helper lymphocytes and macrophages, blocking HIV type-1 growth at multiple stages of the viral life cycle. Fluorescence: max. Abs. l = 341, max. Em. l = 415 (in water)

The Uses of DIDS

ATP transport inhibitor, anion transport inhibitor, antiulcer

The Uses of DIDS

complexing agent for potassium ions

The Uses of DIDS

DIDS is a stilbene sulfonate that inhibits anionic transport. It has been used to inhibit Cl- uptake through plasma membrane-localized Cl- channels in order to study chloride transport. It also effectively inhibits various sodium-coupled bicarbonate transporters.

What are the applications of Application

4,4′-Diisothiocyanatostilbene-2,2′-disulfonic acid disodium salt is a negatively charged homobifunctional cross-linking reagent and dye

What are the applications of Application

DIDS, Disodium Salt is an anion transport inhibitor that inhibits Cl- uptake through plasma membrane-localized Cl- channels.

Storage

Store at +4°C