Dicyclohexano-18-crown-6
Synonym(s):2,3,11,12-Dicyclohexano-1,4,7,10,13,16-hexaoxacyclooctadecane;2,5,8,15,18,21-Hexaoxatricyclo[20.4.0.09.14]hexacosane;2,5,8,15,18,21-Hexaoxatricyclo[20.4.0.09.14] hexacosane, Dicyclohexyl-18-crown-6;Crown ether/Dicyclohexyl-18-crown-6;Dicyclohexyl-18-crown-6
- CAS NO.：16069-36-6
- Empirical Formula: C20H36O6
- Molecular Weight: 372.5
- MDL number: MFCD00005099
- EINECS: 240-216-4
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-01-13 11:20:18
What is Dicyclohexano-18-crown-6?
Chemical properties
White solid
The Uses of Dicyclohexano-18-crown-6
Dicyclohexano is used as an anion activator and complexing agent which solubilizes alkali metal ions in non-polar solvents. It is an important raw material and intermediate used in Organic Synthesis, Pharmaceuticals, Agrochemicals and Dyestuffs etc,.
The Uses of Dicyclohexano-18-crown-6
Anion activator, and complexing agent which solubilizes alkali metal ions in non-polar solvents.
Safety Profile
Poison by ingestion, skin contact, and intraperitoneal routes. An experimental teratogen. An eye and skin irritant. When heated to decomposition it emits acrid smoke and fumes.
Purification Methods
Purify it by chromatography on neutral alumina and eluting with an ether/hexane mixture [see Izatt et al. Inorg Chem 14 3132 1975]. Dissolve it in ether at ca 40o, and spectroscopic grade MeCN is added to the solution, which is then chilled. The crown ether precipitates and is filtered off. It is dried in vacuo at room temperature [Wallace J Phys Chem 89 1357 1985]. [V.gtle ed. Top Corr Chem (Host Guest Complex Chemistry) 98 1981.] SKIN IRRITANT.
Properties of Dicyclohexano-18-crown-6
| Melting point: | 47-50 °C |
| Boiling point: | 344°C |
| Density | 1.102 g/cm |
| refractive index | 1.4909 |
| Flash point: | 113 °C |
| storage temp. | Store below +30°C. |
| form | Crystalline Solid |
| color | White to slightly beige |
| Water Solubility | Slightly soluble |
| Sensitive | Hygroscopic |
| Merck | 14,2602 |
| BRN | 1130529 |
| CAS DataBase Reference | 16069-36-6(CAS DataBase Reference) |
| NIST Chemistry Reference | Dicyclohexano-18-crown-6(16069-36-6) |
| EPA Substance Registry System | Dibenzo[b,k][1,4,7,10,13,16]hexaoxacyclooctadecin, eicosahydro- (16069-36-6) |
Safety information for Dicyclohexano-18-crown-6
| Signal word | Danger |
| Pictogram(s) |
 Skull and Crossbones Acute Toxicity GHS06 |
| GHS Hazard Statements |
H301:Acute toxicity,oral H319:Serious eye damage/eye irritation |
| Precautionary Statement Codes |
P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for Dicyclohexano-18-crown-6
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