Di-tert-butyl disulfide

Synonym(s):tert-Butyl disulfide;Di-tert-butyl disulfide;tert-Butyl disulfide

CAS NO.：110-06-5
Empirical Formula: C8H18S2
Molecular Weight: 178.36
MDL number: MFCD00008838
EINECS: 203-734-1
SAFETY DATA SHEET (SDS)
Update Date: 2026-05-28 05:34:37

What is Di-tert-butyl disulfide?

Chemical properties

clear pale yellow to yellow liquid

The Uses of Di-tert-butyl disulfide

Di-tert-butyl disulfide is used in the preparation of gold-supported thin film from symmetrical and mixed disulphide adsorbates.
Mechanism of the oxidation of di-tert-butyl disulfide in the presence of H2O2 catalyzed by bis(acetylacetonato)oxovanadium and a chiral Schiff-base ligand has been investigated.
Di-tert-butyl disulfide has been used in the preparation of gold-supported thin film from symmetrical and mixed disulphide adsorbates.

The Uses of Di-tert-butyl disulfide

Di-tert-Butyl Disulfide is a general reagent used in the synthesis of a novel neuropeptide Y (NPY) Y5 receptor antagonist Velneperit) used in the treatment of obesity.

What are the applications of Application

Di-tert-butyl disulfide is used in the preparation of gold-supported thin film from symmetrical and mixed disulphide adsorbates

Synthesis Reference(s)

Synthetic Communications, 13, p. 611, 1983 DOI: 10.1080/00397918308059536
Synthesis, p. 669, 1978 DOI: 10.1055/s-1978-24844
Tetrahedron Letters, 31, p. 3591, 1990 DOI: 10.1016/S0040-4039(00)94450-2

General Description

Mechanism of the oxidation of di-tert-butyl disulfide in the presence of H₂O₂ catalyzed by bis(acetylacetonato)oxovanadium and a chiral Schiff-base ligand has been investigated.

Properties of Di-tert-butyl disulfide

Melting point:	-5 °C
Boiling point:	200-201 °C(lit.)
Density	0.923 g/mL at 25 °C(lit.)
vapor density	5 (vs air)
vapor pressure	51.7 mm Hg ( 37.7 °C)
refractive index	n20/D 1.490(lit.)
Flash point:	144 °F
storage temp.	Inert atmosphere,Room Temperature
solubility	Chloroform (Sparingly), Ethanol (Slightly)
form	Liquid
color	Clear pale yellow to yellow
Odor Threshold	0.0018ppm
explosive limit	0.8%(V)
BRN	1698170
CAS DataBase Reference	110-06-5(CAS DataBase Reference)
EPA Substance Registry System	Disulfide, bis(1,1-dimethylethyl) (110-06-5)

Safety information for Di-tert-butyl disulfide

Signal word	Warning
Pictogram(s)	Environment GHS09
GHS Hazard Statements	H411:Hazardous to the aquatic environment, long-term hazard
Precautionary Statement Codes	P273:Avoid release to the environment. P391:Collect spillage. Hazardous to the aquatic environment P501:Dispose of contents/container to..…