dextilidine
- CAS NO.：32447-90-8
- Empirical Formula: C17H23NO2
- Molecular Weight: 273.37
- MDL number: MFCD00868712
- EINECS: 251-048-6
- SAFETY DATA SHEET (SDS)
- Update Date: 2023-07-14 17:48:59
What is dextilidine?
Definition
ChEBI: Dextilidine is an ethyl 2-(dimethylamino)-1-phenylcyclohex-3-ene-1-carboxylate that has S configuration at the carbon bearing the phenyl group and R configuration at the carbon bearing the dimethylamino group. The opioid analgesic tilidine is the racemate comprising equimolar amounts of dextilidine and its enantiomer, ent-dextilidine. A prodrug, tilidine is converted by the liver to the active analgesic, nortilidine; virtually all of the opioid activity resides in the (1S,2R) isomer (i.e. the isomer derived from dextilidine). It has a role as an opioid analgesic and a prodrug. It is an enantiomer of an ent-dextilidine.
Properties of dextilidine
| Melting point: | 56-58 °C |
| Boiling point: | 354.2±42.0 °C(Predicted) |
| Density | 1.06±0.1 g/cm3(Predicted) |
| pka | 8.26±0.40(Predicted) |
Safety information for dextilidine
Computed Descriptors for dextilidine
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