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HomeProduct name listDELTA-AMINOVALERYL-PHE-PHE-PRO-N-ME-LEU-MET-NH2

DELTA-AMINOVALERYL-PHE-PHE-PRO-N-ME-LEU-MET-NH2

DELTA-AMINOVALERYL-PHE-PHE-PRO-N-ME-LEU-MET-NH2 Structural

What is DELTA-AMINOVALERYL-PHE-PHE-PRO-N-ME-LEU-MET-NH2?

The Uses of DELTA-AMINOVALERYL-PHE-PHE-PRO-N-ME-LEU-MET-NH2

GR 73632 is a NK1 tachykinin receptor agonist used in the treatment of asthma and gastrointestinal disorders. It is involved in the contraction of muscles.

General Description

Neurokinin (NK) receptors are acted upon by tachykinins or neurokinins namely, NKA and NKB. These are endogenous ligands. An exogenous agonist/ligand for NK1 is GR 64349 petpide.

Biochem/physiol Actions

GR 73632 interacts with neurokinin (NK1) receptor, which results in rhythmic tapping of hind-foot in gerbils. Administration of this peptide in the intra-ventral tegmental area (VTA) results in locomotor activity. It interacts with and activates NK1 receptors present on smooth muscle and interstitial cells of Cajal, resulting in elevated distention-induced peristalsis.

Storage

Store at -20°C

Properties of DELTA-AMINOVALERYL-PHE-PHE-PRO-N-ME-LEU-MET-NH2

Boiling point: 1082.2±65.0 °C(Predicted)
Density  1.198±0.06 g/cm3(Predicted)
storage temp.  -20°C
solubility  Water:1.0(Max Conc. mg/mL);1.31(Max Conc. mM)
pka 13.34±0.46(Predicted)
form  Powder
color  White to off-white
Water Solubility  Soluble to 1 mg/ml in water

Safety information for DELTA-AMINOVALERYL-PHE-PHE-PRO-N-ME-LEU-MET-NH2

Computed Descriptors for DELTA-AMINOVALERYL-PHE-PHE-PRO-N-ME-LEU-MET-NH2

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