DCB
- CAS NO.:6971-97-7
- Empirical Formula: C14H10Cl2N2
- Molecular Weight: 277.15
- MDL number: MFCD00556081
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-07-09 12:03:46
What is DCB?
The Uses of DCB
DCB is an allosteric ligand for mGluR-5 (1). Regulates glutamate concentration however may induce neuronal damage through cerebral ischemia (2).
What are the applications of Application
DCB is an allosteric ligand for mGluR-5
Biological Activity
Allosteric ligand for the metabotropic glutamate receptor mGlu 5 ; displays neutral modulation. Does not affect agonist-stimulated mGlu 5 responses, but blocks regulation of the receptor by other allosteric modulators such as DFB ([(3-Fluorophenyl)methylene]hydrazone-3-fluorobenzaldehyde ) and DMeOB ([(3-Methoxyphenyl)methylene]hydrazone-3-methoxybenzaldehyde ).
Properties of DCB
| Melting point: | 40 °C |
| Boiling point: | 387.8±42.0 °C(Predicted) |
| Density | 1.21±0.1 g/cm3(Predicted) |
| storage temp. | 2-8°C |
| solubility | DMSO: ~6.8 mg/mL |
| form | solid |
| pka | 5.84±0.50(Predicted) |
| color | yellow |
Safety information for DCB
| Signal word | Danger |
| Pictogram(s) |
![]() Corrosion Corrosives GHS05 ![]() Exclamation Mark Irritant GHS07 ![]() Environment GHS09 |
| GHS Hazard Statements |
H302:Acute toxicity,oral H315:Skin corrosion/irritation H317:Sensitisation, Skin H318:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation H410:Hazardous to the aquatic environment, long-term hazard |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P273:Avoid release to the environment. P280:Wear protective gloves/protective clothing/eye protection/face protection. P301+P312:IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for DCB
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