DBCO-sulfo-NHS ester
Synonym(s):DBCO-sulfo-NHS ester;DBCO-sulfo-SE
- CAS NO.：1400191-52-7
- Empirical Formula: C25H23N2NaO8S
- Molecular Weight: 534.51
- MDL number: MFCD22572669
- Update Date: 2026-04-21 10:31:43
What is DBCO-sulfo-NHS ester?
Description
DBCO-Sulfo-NHS ester is a water-soluble sulfocated reagent containing DBCO moiety. It can be used for simple and efficient labeling of antibodies, proteins and any other primary amine-bearing macromolecules with DBCO moiety in 100% aqueous buffers. DBCO is commonly used for copper-free Click Chemistry reactions.
The Uses of DBCO-sulfo-NHS ester
Dibenzocyclooctyne-sulfo-N-hydroxysuccinimidyl ester may be used for the covalent modification of nano-sized metal-organic frameworks (NMOFs) with nucleic acids via click chemistry during the synthesis stimuli-responsive DNA-gated NMOFs. These NMOFs can act as carriers of a fluorescent agent or anticancer drug, making them highly useful in targeted drug release system.
Properties of DBCO-sulfo-NHS ester
| Melting point: | 240-260 °C |
| storage temp. | -20°C |
| form | Solid |
| color | Off-white to yellow |
Safety information for DBCO-sulfo-NHS ester
Computed Descriptors for DBCO-sulfo-NHS ester
| InChIKey | NSZPURPXEZOXPC-UHFFFAOYSA-N |
| SMILES | C(N1CC2=CC=CC=C2C#CC2=CC=CC=C12)(=O)CCCCC(=O)ON1C(CC(S(O)(=O)=O)C1=O)=O.[NaH] |
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