D13
- CAS NO.：321945-27-1
- Empirical Formula: C14H9Br3N2O2
- Molecular Weight: 476.94
- Update Date: 2026-05-11 19:39:08
What is D13?
Description
D13 is an acylhydrazone antifungal.1 It is active against C. neoformans in vitro (MIC80 = 0.06 μg/ml). D13 (20 mg/kg per day, p.o.) increases survival in mouse models of C. neoformans, C. albicans, or A. fumigatus infection.
References
1. Lazzarini, C., Haranahalli, K., Rieger, R., et al. Acylhydrazones as antifungal agents targeting the synthesis of fungal sphingolipids Antimicrob. Agents Chemother. 62(5),e00156-00118(2018).
Properties of D13
| Density | 1.96±0.1 g/cm3(Predicted) |
| storage temp. | Store at -20°C |
| solubility | DMF: 30 mg/ml; DMSO: 10 mg/ml |
| form | A crystalline solid |
| pka | 6.03±0.50(Predicted) |
Safety information for D13
Computed Descriptors for D13
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