D-Penicillamine disulfide
Synonym(s):S,S′-Bi(D -penicillamine);3,3′-Dithiobis(2-amino-3-methylbutanoic acid);3,3′-Dithiobis(2-amino-3-methylbutyric acid);3,3′-Dithiobis-D -valine;NSC 87505
- CAS NO.:20902-45-8
- Empirical Formula: C10H20N2O4S2
- Molecular Weight: 296.41
- MDL number: MFCD00004264
- EINECS: 244-107-2
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-09-12 18:52:45
What is D-Penicillamine disulfide?
The Uses of D-Penicillamine disulfide
D-Penicillamine Disulfide is used in the treatment of neurodegenerative diseases such as Parkinson’s and Motor Neuron Disease. Inactivator of α1-antiproteinase, preventing deleterious effects of peroxynitrite.
Definition
ChEBI: An organic disulfide consisting of two D-penicillamines joined by a disulfide bond.
Properties of D-Penicillamine disulfide
| Melting point: | 204 °C (dec.)(lit.) |
| alpha | D23 +27° (c = 1.46 in 1N HCl) |
| Boiling point: | 467.0±45.0 °C(Predicted) |
| Density | 1.353±0.06 g/cm3(Predicted) |
| storage temp. | 2-8°C |
| solubility | Aqueous Base (Slightly), Water (Slightly) |
| form | neat |
| pka | 1.76±0.12(Predicted) |
| color | White to Off-White |
| optical activity | [α]25/D 75°, c = 1 in 1 M NaOH |
| Merck | 13,7161 |
| BRN | 4461521 |
| Stability: | Hygroscopic |
Safety information for D-Penicillamine disulfide
| Signal word | Warning |
| Pictogram(s) |
![]() Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for D-Penicillamine disulfide
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