D(-)-Norvaline
Synonym(s):(R)-(−)-2-Aminopentanoic acid
- CAS NO.：2013-12-9
- Empirical Formula: C5H11NO2
- Molecular Weight: 117.15
- MDL number: MFCD00008097
- EINECS: 217-936-2
- SAFETY DATA SHEET (SDS)
- Update Date: 2025-06-01 17:50:27
What is D(-)-Norvaline?
Chemical properties
white to off-white crystals or crystalline powder
The Uses of D(-)-Norvaline
D-Norvaline is used as a catalyst in the enantioselective α-bromination of carbonyl and 1,3-dicarbonyl compounds. D-Norvaline is also incorporated into jadomycins (a group of compounds that are widely used as antibiotics), ultimately producing compounds that have potential antiproliferative/anti-cancer properties.
Definition
ChEBI: D-2-aminopentanoic acid is a 2-aminopentanoic acid that has R-configuration. It has a role as an EC 6.1.1.4 (leucine--tRNA ligase) inhibitor. It is a D-alpha-amino acid and a 2-aminopentanoic acid. It is an enantiomer of a L-2-aminopentanoic acid.
Properties of D(-)-Norvaline
| Melting point: | >300 °C(lit.) |
| Boiling point: | 222.9±23.0 °C(Predicted) |
| alpha | -24 º (c=5, 5N HCl) |
| Density | 1.2000 (estimate) |
| refractive index | -25 ° (C=10, 6mol/L HCl) |
| storage temp. | Store at RT. |
| solubility | Aqueous Acid (Slightly), Water (Slightly) |
| form | Solid |
| pka | 2.54±0.20(Predicted) |
| color | White to Off-White |
| optical activity | [α]20/D 24°, c = 10 in 5 M HCl |
| Water Solubility | SOLUBLE |
| Merck | 14,6716 |
| BRN | 1721161 |
| CAS DataBase Reference | 2013-12-9(CAS DataBase Reference) |
Safety information for D(-)-Norvaline
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation |
| Precautionary Statement Codes |
P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P332+P313:IF SKIN irritation occurs: Get medical advice/attention. P337+P313:IF eye irritation persists: Get medical advice/attention. |
Computed Descriptors for D(-)-Norvaline
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