D-(+)-Norephedrine
Synonym(s):(1S,2R)-2-Amino-1-phenyl-1-propanol;erythro-α-(1-aminoethyl)benzyl alcohol;D -(+)-Norephedrine;Phenylpropanolamine
- CAS NO.：37577-28-9
- Empirical Formula: C9H13NO
- Molecular Weight: 151.21
- MDL number: MFCD00064411
- EINECS: 628-077-1
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-05-28 06:05:11
What is D-(+)-Norephedrine?
The Uses of D-(+)-Norephedrine
(1S,2R)-(+)-Norephedrine Hydrochloride is used in preparation of pyrrolopyridines as ERK inhibitors useful in treatment of diseases.
Definition
ChEBI: (+)-norephedrine is an amphetamine that is propylbenzene substituted by a hydroxy group at position 1 and by an amino group at position 2 (the 1S,2R-stereoisomer). It is a member of amphetamines and a phenethylamine alkaloid.
Properties of D-(+)-Norephedrine
| Melting point: | 51-54 °C(lit.) |
| Boiling point: | 288.1±20.0 °C(Predicted) |
| alpha | 40 º (c=7, 1M HCl) |
| Density | 1.071±0.06 g/cm3(Predicted) |
| Flash point: | >230 °F |
| storage temp. | 2-8°C |
| pka | 12.07±0.45(Predicted) |
| optical activity | [α]20/D +40°, c = 7 in 1 M HCl |
| BRN | 2802896 |
| CAS DataBase Reference | 37577-28-9(CAS DataBase Reference) |
| NIST Chemistry Reference | (1S,2r)-(+)-norephedrine(37577-28-9) |
Safety information for D-(+)-Norephedrine
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H302:Acute toxicity,oral H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for D-(+)-Norephedrine
D-(+)-Norephedrine manufacturer
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