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HomeProduct name listD-ERYTHRO-C20-DIHYDROSPHINGOSINE

D-ERYTHRO-C20-DIHYDROSPHINGOSINE

D-ERYTHRO-C20-DIHYDROSPHINGOSINE Structural

What is D-ERYTHRO-C20-DIHYDROSPHINGOSINE?

Description

Sphinganine (d20:0) is a natural isomer of dihydro-D-erythro-sphinganine (sphinganine (d18:0); ) that is a precursor of ceramide and sphingosine as well as a substrate for sphingosine kinases, which generate sphingosine-1-phosphate (d18:1) . In S. cerevisiae, the amount of sphinganine (d20:0) increases 10.8-fold in response to heat stress, indicating it is involved in heat stress adaptation. Sphinganine levels increase significantly in response to certain mycotoxins, including fumonisins as well as in some cancers. Sphinganine can block protein kinase C activation in some cases but not others. [Matreya, LLC. Catalog No. 1845]

The Uses of D-ERYTHRO-C20-DIHYDROSPHINGOSINE

Sphinganine-C20 is a sphingolipid that plays an important role in the regulation of central cellular processes, including cell growth, survival and differentiation.

Definition

ChEBI: A 2-aminoicosane-1,3-diol having (2S,3R)-configuration.

Properties of D-ERYTHRO-C20-DIHYDROSPHINGOSINE

Boiling point: 471.9±25.0 °C(Predicted)
Density  0.920±0.06 g/cm3(Predicted)
storage temp.  Store at -20°C
solubility  Chloroform:Methanol (5:1): soluble; Ethanol: soluble, warmed
form  A solid
pka 12.57±0.45(Predicted)

Safety information for D-ERYTHRO-C20-DIHYDROSPHINGOSINE

Computed Descriptors for D-ERYTHRO-C20-DIHYDROSPHINGOSINE

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