D(-)-allo-Threonine

CAS NO.：24830-94-2
Empirical Formula: C4H9NO3
Molecular Weight: 119.12
MDL number: MFCD00004526
EINECS: 246-488-0
SAFETY DATA SHEET (SDS)
Update Date: 2026-05-28 02:50:34

What is D(-)-allo-Threonine?

Chemical properties

white crystalline powder

The Uses of D(-)-allo-Threonine

They are found as constituents of an increasing group of biologically active peptides. Stereocontrolled syntheses of chiral and racemic key intermediates to thienamycin from d-allo-threonine and trans-crotonic acid.

Definition

ChEBI: D-allothreonine is the D-enantiomer of allothreonine. It occurs as a component of peptido-lipids in certain bacteria. It has a role as a bacterial metabolite. It is an allothreonine and a D-alpha-amino acid. It is an enantiomer of a L-allothreonine. It is a tautomer of a D-allothreonine zwitterion.

Purification Methods

Recrystallise D-allothreonine from aqueous EtOH or 50% EtOH. [Elliot J Chem Soc 62 1950, Birnbaum et al. J Biol Chem 194 455 1952, IR: Greenstein & Winitz The Chemistry of the Amino Acids J. Wiley, Vol 3 1961, Beilstein 4 IV 3170.]

Properties of D(-)-allo-Threonine

Melting point:	276 °C (dec.)(lit.)
Boiling point:	222.38°C (rough estimate)
alpha	-33.5 º (c=1, 1N HCl 24 ºC)
Density	1.3126 (rough estimate)
refractive index	-10 ° (C=5, H2O)
storage temp.	Keep in dark place,Inert atmosphere,Room temperature
solubility	Water (Slightly)
form	Solid
pka	2.19±0.10(Predicted)
color	White to Off-White
Water Solubility	soluble
BRN	1721644
CAS DataBase Reference	24830-94-2(CAS DataBase Reference)
NIST Chemistry Reference	D-allothreonine(24830-94-2)

Safety information for D(-)-allo-Threonine

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation
Precautionary Statement Codes	P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.