CYCLOPROPANECARBOTHIOAMIDE
- CAS NO.：20295-34-5
- Empirical Formula: C4H7NS
- Molecular Weight: 101.17
- MDL number: MFCD09469287
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-01-13 11:13:05
What is CYCLOPROPANECARBOTHIOAMIDE?
Description
Cyclopropanecarbothioamide is used for purification of thiazolo [5, 4-b] pyridine-and thiazolo [5, 4-c] pyridine derivatives from chloronitropyridines and thioamides, or thioureas during the simple-step reaction. It is also a useful chemical during the proteomics study. Recent study has also used it for synthesis of a novel heterocyclic compound, CE-125, which can improve working memory in the radial arm maze and modulate the dopamine receptor D1R in frontal cortex of the Sprague-Dawley rat.
The Uses of CYCLOPROPANECARBOTHIOAMIDE
Cyclopropanecarbothioamide is used for purification in single-step preparation of thiazolo [5, 4-b] pyridine-and thiazolo [5, 4-c] pyridine derivatives from chloronitropyridines and thioamides, or thioureas.
References
https://www.alfa.com/en/catalog/H32315/
Hussein, A. M., et al. "A novel heterocyclic compound improves working memory in the radial arm maze and modulates the dopamine receptor D1R in frontal cortex of the Sprague-Dawley rat." Behavioural Brain Research 332(2017):308-315.
Properties of CYCLOPROPANECARBOTHIOAMIDE
| Melting point: | 111-113℃ |
| Boiling point: | 176.9±23.0 °C(Predicted) |
| Density | 1.272±0.06 g/cm3(Predicted) |
| pka | 13.19±0.20(Predicted) |
| CAS DataBase Reference | 20295-34-5 |
Safety information for CYCLOPROPANECARBOTHIOAMIDE
| Signal word | Warning |
| Pictogram(s) |
 Skull and Crossbones Acute Toxicity GHS06 |
| GHS Hazard Statements |
H301:Acute toxicity,oral |
| Precautionary Statement Codes |
P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P270:Do not eat, drink or smoke when using this product. P321:Specific treatment (see … on this label). P405:Store locked up. |
Computed Descriptors for CYCLOPROPANECARBOTHIOAMIDE
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