CRT-0066101
- CAS NO.：956123-34-5
- Empirical Formula: C18H22N6O
- Molecular Weight: 338.41
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-05-28 04:44:14
What is CRT-0066101?
Biochem/physiol Actions
CRT0066101 is a very potent inhibitor of Protein Kinase D (PKD) isoforms with IC50 values for PKD-1, -2 and -3 = 1, 2.5 and 2 nM, respecitively. CRT0066101 has been shown to have anticancer activity. CRT0066101 potently inhibits proliferation of PANC-1 pancreatic cells, and blocks migration and invasion of U87MG glioblastoma cells. CRT0066101 has also been shown to decrease growth of primary tumors and metastasis of ER(-) breast cancers.
Properties of CRT-0066101
| Boiling point: | 518.5±50.0 °C(Predicted) |
| Density | 1.30±0.1 g/cm3(Predicted) |
| storage temp. | -20°C |
| form | powder |
| pka | 8.10±0.50(Predicted) |
| color | white to beige |
Safety information for CRT-0066101
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H302:Acute toxicity,oral |
Computed Descriptors for CRT-0066101
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