CROCONAZOLE
- CAS NO.：77175-51-0
- Empirical Formula: C18H15ClN2O
- Molecular Weight: 310.78
- MDL number: MFCD00865578
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-04-21 10:31:43
What is CROCONAZOLE?
The Uses of CROCONAZOLE
Cloconazole is an antifungal azole drug.
Definition
ChEBI: Croconazole is an imidazole antifungal drug, a conazole antifungal drug, a member of monochlorobenzenes and an aromatic ether.
Indications
Topical treatment of mycoses of the skin induced or sustained by fungi such as dermatophytes and yeasts.
Antimicrobial activity
Broad-spectrum imidazole antimycotic with activity against almost all pathogenic fungi.
Side Effects
Local irritations and allergic reactions after topical treatment may occur in rare cases and are mainly due to the galenic formulation.
Metabolic pathway
When male rabbits are administered croconazole by intravenous injection, as many as 16 metabolites are excreted in the urine and 13 metabolites are identified. The biotransformation reaction of croconazole includes ring hydroxylation, O-dechlorobenzylation, and the loss of the imidazole ring.
Properties of CROCONAZOLE
| Melting point: | 72-73℃ |
| Boiling point: | 501.5±60.0 °C(Predicted) |
| Density | 1.16 |
| storage temp. | 2-8°C |
| pka | 6.29±0.10(Predicted) |
Safety information for CROCONAZOLE
Computed Descriptors for CROCONAZOLE
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