CONIFERYL ALCOHOL
Synonym(s):3-(4-Hydroxy-3-methoxyphenyl)-2-propen-1-ol;4-Hydroxy-3-methoxycinnamyl alcohol
- CAS NO.:458-35-5
- Empirical Formula: C10H12O3
- Molecular Weight: 180.2
- MDL number: MFCD00002922
- EINECS: 207-277-9
- SAFETY DATA SHEET (SDS)
- Update Date: 2025-12-05 14:33:18
What is CONIFERYL ALCOHOL?
Chemical properties
beige crystalline powder
Physical properties
White (colorless) crystals. M.P. 74°C. Very slightly soluble in water, soluble in alcohol and oils.
The Uses of CONIFERYL ALCOHOL
Coniferyl alcohol was used as a fungal growth inhibitor.
Definition
ChEBI: A phenylpropanoid that is one of the main monolignols, produced by the reduction of the carboxy functional group in cinnamic acid and the addition of a hydroxy and a methoxy substituent to the aromatic ring.
What are the applications of Application
CONIFERYL ALCOHOL can polymerize with weak mineral acids and certain organic acids, turning into an amorphous, odorless gum. This chemical could find extensive use as a fixative and blender in various types of floral, balsamic and Oriental fragrances. However, it is not generally available in the state of chemical or olfactory purity desirable to the perfumer.
General Description
Coniferyl alcohol is one of the preferred substrate of the eucalpytus globus enzyme.
Purification Methods
It is soluble in EtOH and insoluble in H2O. It can, however, be recrystallised from EtOH and distilled in a vacuum. It polymerises in dilute acid. The benzoyl derivative has m 95-96o (from pet ether), and the tosylate has m 66o. [Derivatives: Freudenberg & Achtzehn Chem Ber 88 10 1955, UV: Herzog & Hillmer Chem Ber 64 1288 1931, Beilstein 6 II 1093.]
Properties of CONIFERYL ALCOHOL
| Melting point: | 75-80 °C(lit.) |
| Boiling point: | 163-165 °C3 mm Hg(lit.) |
| Density | 1.1272 (rough estimate) |
| RTECS | SL5367000 |
| refractive index | 1.5080 (estimate) |
| Flash point: | 163-165°C/3mm |
| storage temp. | -20°C |
| solubility | alcohol: moderately soluble(lit.) |
| pka | 9.99±0.35(Predicted) |
| form | Solid |
| color | Pale Yellow to Light Yellow |
| Sensitive | Light Sensitive |
| Merck | 14,2504 |
| BRN | 2048961 |
| Stability: | Light Sensitive |
| CAS DataBase Reference | 458-35-5(CAS DataBase Reference) |
| EPA Substance Registry System | Phenol, 4-(3-hydroxy-1-propenyl)-2-methoxy- (458-35-5) |
Safety information for CONIFERYL ALCOHOL
| Signal word | Warning |
| Pictogram(s) |
![]() Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H302:Acute toxicity,oral H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H332:Acute toxicity,inhalation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P280:Wear protective gloves/protective clothing/eye protection/face protection. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for CONIFERYL ALCOHOL
| InChIKey | JMFRWRFFLBVWSI-UHFFFAOYSA-N |
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