Colestipol
- CAS NO.：50925-79-6
- Empirical Formula: C11H28ClN5O
- Molecular Weight: 0
What is Colestipol?
The Uses of Colestipol
Colestipol is used for hypercholesterolemia (including atherosclerosis and arterial hypertension).
Mechanism of action
Colestipol binds to bile acids, which are secreted from the organism in a form which bunds to the ion-exchange resin. It lowers the overall level of cholesterol and cholesterol-containing low-density lipoproteins in blood plasma while not affecting the level of high-density lipoproteins.
Synthesis
Colestipol (20.1.1) is a hydrochloride of the product of copolymerization of epichlorohydrine with diethylentriamine that contains varying numbers of quaternary nitrogen atoms. There is no exact formula of the product of copolymerization, but its approximate structure can be expressed as 20.1.1.
Safety information for Colestipol
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