CINCHONINE HYDROCHLORIDE
- CAS NO.：5949-11-1
- Empirical Formula: C19H23ClN2O
- Molecular Weight: 330.85
- MDL number: MFCD00079070
- EINECS: 621-239-2
- SAFETY DATA SHEET (SDS)
- Update Date: 2023-05-18 11:31:14
What is CINCHONINE HYDROCHLORIDE?
Description
Cinchonine hydrochloride not only possesses the required solubility and bioavailability criteria for pharmaceutical formulations while retaining desired therapeutic properties, but is also very stable in solution, which facilitates the preparation of aqueous formulations, especially injections.
The Uses of CINCHONINE HYDROCHLORIDE
Cinchonine hydrochloride can be used as an inhibitory substance for the phenomenon of "multidrug resistance" (MDR). In particular, cinchonine hydrochloride compositions are useful in the treatment of cancer-related diseases with MDR phenomena.
Biological Activity
Cinchonine hydrochloride ((8R,9S)-Cinchonine hydrochloride) is a natural compound in cinchona bark with antimalarial activity. It can activate endoplasmic reticulum stress to induce apoptosis in human hepatoma cells.
Properties of CINCHONINE HYDROCHLORIDE
| Melting point: | 208-218 °C(lit.) |
| storage temp. | under inert gas (nitrogen or Argon) at 2-8°C |
| CAS DataBase Reference | 5949-11-1 |
Safety information for CINCHONINE HYDROCHLORIDE
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P270:Do not eat, drink or smoke when using this product. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection. P501:Dispose of contents/container to..… |
Computed Descriptors for CINCHONINE HYDROCHLORIDE
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