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HomeProduct name listCID 16020046

CID 16020046

Synonym(s):4-[4,6-Dihydro-4-(3-hydroxyphenyl)-3-(4-methylphenyl)-6-oxopyrrolo[3,4-c]pyrazol-5(1H)-yl]-benzoic acid

CID 16020046 Structural

What is CID 16020046?

The Uses of CID 16020046

CID 16020046 is a selective GPR55 antagonist. It Inhibits LPI-induced Ca2+ signaling, ERK1/2 phosphorylation and GPR55-mediated transcription factor activation. It displays weak inhibition of acetylcholinesterase, μ-opioid receptor, KCNH2 and hERG. It decreases LPI-induced GPR55 internalization.

Biochem/physiol Actions

CID16020046 is a potent and a selective GPR55 antagonist that inhibits GPR55-mediated ERK1/2 phosphorylation. CID16020046 inhibits LPI-induced Ca2+ signaling in HEK-GPR55 cells.

Storage

Store at +4°C

Properties of CID 16020046

Boiling point: 748.1±60.0 °C(Predicted)
Density  1.425±0.06 g/cm3(Predicted)
storage temp.  2-8°C
solubility  DMSO: soluble1mg/mL, clear (warmed)
pka 4.27±0.10(Predicted)
form  powder
color  white to beige

Safety information for CID 16020046

Signal word Warning
Pictogram(s)
ghs
Exclamation Mark
Irritant
GHS07
GHS Hazard Statements H315:Skin corrosion/irritation
H319:Serious eye damage/eye irritation
Precautionary Statement Codes P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Computed Descriptors for CID 16020046

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