CHOLIC-2,2,4,4-D4 ACID
- CAS NO.：116380-66-6
- Empirical Formula: C24H36D4O5
- Molecular Weight: 412.6
- MDL number: MFCD00209701
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-01-13 11:13:01
What is CHOLIC-2,2,4,4-D4 ACID?
Description
Cholic acid-d4 is intended for use as an internal standard for the quantification of cholic acid by GC- or LC-MS. Cholic acid is a primary bile acid. It is formed from cholesterol via a multistep process catalyzed by the cytochrome P450 (CYP) isoforms CYP7A1, CYP8B1, and CYP27A1. Cholic acid is conjugated to glycine or taurine by bile acid-CoA:amino acid N-acyltransferase (BAAT) to produce glycocholic acid (GCA; ) and taurocholic acid (TCA; ), respectively, in the liver, and is transformed into the secondary bile acid deoxycholic acid (DCA; ) by intestinal microbiota. It induces C. difficile colony formation in an agar dilution assay when used at a concentration of 0.1% w/v. Dietary administration of cholic acid (0.4% w/w) increases serum cholesterol levels, biliary phospholipid secretion, and fecal DCA levels in rats.
The Uses of CHOLIC-2,2,4,4-D4 ACID
Cholic Acid-d4 is a labelled analog of Cholic acid (C432600) which is a choleretic produced by, and isolated from liver cells.
Definition
ChEBI: Cholic acid-2,2,4,4-d4 is a bile acid.
Properties of CHOLIC-2,2,4,4-D4 ACID
| Melting point: | 200-201°C (lit.) |
| storage temp. | Store at -20°C |
| solubility | DMF: 30 mg/ml,DMF:PBS(pH 7.2)(1:1): 0.5 mg/ml,DMSO: 20 mg/ml,Ethanol: 20 mg/ml |
| form | Solid |
| color | White to Off-White |
Safety information for CHOLIC-2,2,4,4-D4 ACID
Computed Descriptors for CHOLIC-2,2,4,4-D4 ACID
New Products
DL-beta-(3-Bromophenyl)alanine Tetrabutylammonium perchlorate N,O-Dimethylhydroxylamine hydrochloride (RS)-beta-Amino-beta-(4-bromophenyl)propionic acid 2-Amino-5-bromo-4-(trifluoromethyl)pyridine（RM for Indian lab) N,N CARBONYL DIIMIDAZOLE Levothyroxine Impurity-F Montelukast EP Impurity-D/Montelukast USP Related Compound C Atorvastatin FXA Impurity/Atorvastatin Cyclic 6-Hydroxy Impurity Sodium Salt Isosulfan blue Keto N-Oxide Impurity Ivermectin Impurity F N-Nitroso des Methyl Tramadol/N-Nitroso-N-Desmethyl-Tramadol (R)-BoroLeu-(+)-Pinanediol-CF3COOH 1,4-bis(methylsulfonyl)butane 4-(5-amino-1-methyl-1h-benzoimidazol-2-yl)-butyric acid isopropyl ester. 5-Methyl-1,3-benzenediacetonitrile 4-Fluorothiophenol 1-methyl amino-2,4-dinitro benzene CSA (DL-10-Camphorsulfonic Acid) 2-Hydroxy-4-methylnicotinic acid 3-iodo-1H-pyrazolo[3,4-d]pyrimidin-4-amine (2S)-1-((2S,3S)-3-(2-methylbutyl)-4-oxooxetan-2-yl)pentadecan-2-yl formylleucinate 1-(3,5-dichlorophenyl)-2,2,2-trifluoroethane-1-sulfonyl chloride S-(1-(3,5-dichlorophenyl)-2,2,2-trifluoroethyl) ethanethioateRelated products of tetrahydrofuran
You may like
-
Cholic acid-d4 CAS 116380-66-6View Details
116380-66-6 -
674783-97-2 98+View Details
674783-97-2 -
H-D-TRP(FOR)-OH HCL 98+View Details
367453-01-8 -
DL-beta-(3-Bromophenyl)alanine 117391-50-1 98+View Details
117391-50-1 -
49830-37-7 98+View Details
49830-37-7 -
3-Amino-3-(4-fluorophenyl)propanoic acid 98+View Details
325-89-3 -
1428243-26-8 98+View Details
1428243-26-8 -
1-aminocyclopentane carbonitrile, HCl 98+View Details
16195-83-8