Chloropyramine
- CAS NO.：59-32-5
- Empirical Formula: C16H20ClN3
- Molecular Weight: 289.8
- MDL number: MFCD00065266
- EINECS: 200-421-1
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-05-28 04:50:52
What is Chloropyramine?
The Uses of Chloropyramine
Chloropyramine is used for allergic dermatosis, allergic rhinitis and conjunctivitis, for drug-induced allergies, in the beginning stages of bronchial asthma, eczema, neurodermatitis, contact dermatitis, and toxicodermia. It also exhibits a sedative effect. Synonyms of this drug are suprastin, chlortripelenamine, and synopen.
Definition
ChEBI: N'-[(4-chlorophenyl)methyl]-N,N-dimethyl-N'-(2-pyridinyl)ethane-1,2-diamine is an aminopyridine.
Synthesis
Chloropyramine, N-(4-chlorobenzyl)-N??,N??-dimethyl-N-2-pyridylethylenediamine (16.1.9), is synthesized in a somewhat different manner, which is by reacting 2-brompyridine with N-(4-chlorobenzyl)-N??,N??-dimethylethylenediamine (16.1.8). N-(4-Chlorobenzyl)-N??,N??-dimethylethylenediamine (16.1.8), in turn, is synthesized by condensation of 4-chlorobenzaldehyde c N,N-dimethylethylenediamine with subsequent reduction of the imine group.
Properties of Chloropyramine
| Melting point: | 25°C |
| Boiling point: | bp0.2 154-155° |
| Density | 1.1031 (rough estimate) |
| refractive index | 1.6010 (estimate) |
| pka | 9.00±0.28(Predicted) |
| NIST Chemistry Reference | Chloropyramine(59-32-5) |
Safety information for Chloropyramine
Computed Descriptors for Chloropyramine
New Products
N-Carbethoxy-4-piperidone 1-Aminocyclopentane carbonitrile Tetrabutylammonium perchlorate N,O-Dimethylhydroxylamine hydrochloride (RS)-beta-Amino-beta-(4-bromophenyl)propionic acid 2-Amino-5-bromo-4-(trifluoromethyl)pyridine N-Vinylformamide 4 pentyn 1 ol Phenethyl cinnamate Dipropyl disulfide Ethyl 3-phenylpropanoate β-Bromostyrene Methacrylate-PEG-Methacrylate, Mn:35000 2,4-Dihydroxyacetophenone 2-Chloro 5-Fluoro Pyridine Vasicinone 2-Chloroisonicotinic Acid Tween 80 or Polysorbate 80 5-Bromo-1-Pentyne 1-(2-Methyl-5-nitrophenyl)guanidine Nitrate Methyl trans-4-Aminocyclohexanecarboxylate Hydrochloride N-(4-Cyano-3-(trifluoromethyl)phenyl)-2-methyloxirane-2-carboxamide 2-Pentyn-1-oL 4-NitrobenzotrifluorideRelated products of tetrahydrofuran
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