Chloroacetamido-PEG4-t-Butyl Ester

CAS NO.：1365655-90-8
Empirical Formula: C17H32ClNO7
Molecular Weight: 397.89
MDL number: MFCD22056319
Update Date: 2026-05-28 06:27:48

What is Chloroacetamido-PEG4-t-Butyl Ester?

Description

Chloroacetamido-PEG4-t-Butyl Ester is a PEG linker containing a chloroacetamide and a t-butyl ester. The chlorine is a good leaving group and can undergo substitution reactions. The t-butyl group is an acid labile protecting group. Upon removal, the carboxylic acid can be further reacted. The hydrophilic PEG chain increases the water solubilty of compounds in aqueous media.

Properties of Chloroacetamido-PEG4-t-Butyl Ester

Boiling point:	527.6±50.0 °C(Predicted)
Density	1.119±0.06 g/cm3(Predicted)
pka	13.57±0.46(Predicted)
form	Liquid
color	Colorless to light yellow

Safety information for Chloroacetamido-PEG4-t-Butyl Ester

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H302:Acute toxicity,oral H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes	P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Computed Descriptors for Chloroacetamido-PEG4-t-Butyl Ester

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