Chloroacetamide
Synonym(s):2-Chloroacetamide
- CAS NO.：79-07-2
- Empirical Formula: C2H4ClNO
- Molecular Weight: 93.51
- MDL number: MFCD00008027
- EINECS: 201-174-2
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-04-22 18:57:36
What is Chloroacetamide?
Description
Chloroacetamide is a preservative used in several applications such as in cutting metalwork fluids, in paints or in glues. It can induce contact dermatitis in hairdressers, or in shoemakers when used as a leather preservative.
Chemical properties
white crystalline powder
The Uses of Chloroacetamide
2-Chloroacetamide is used as surface-active agent in home laundry, cleaning products & household formulated cleaners, other industrial uses, petroleum production, polymer processing.
The Uses of Chloroacetamide
A component of herbicidal mixtures of cellulose biosynthesis inhibitors with VLCFA inhibitors.
The Uses of Chloroacetamide
preservative in cosmetic and pharmaceutical creams, shampoos, bath lotions, etc.; preservative in glues, cooling fluids.
Flammability and Explosibility
Non flammable
Contact allergens
Chloroacetamide as a preservative is used in several applications as in cutting metalworking fluids, in paints or in glues. It can induce contact dermatitis in hairdressers or in shoemakers, being used as a leather preservative.
Safety Profile
Poison by ingestion, intravenous, and intraperitoneal routes. Mutation data reported. When heated to decomposition it emits very toxic Cland NOx. See also N-CHLOROACETAMIDE.
Purification Methods
Recrystallise the amide from acetone and dry it under vacuum over P2O5. [Beilstein 2 IV 490.]
Properties of Chloroacetamide
| Melting point: | 116-118 °C(lit.) |
| Boiling point: | 224.5 °C |
| Density | 0.84 |
| vapor pressure | 0.05 mm Hg ( 20 °C) |
| refractive index | 1.4480 (estimate) |
| Flash point: | 170 °C |
| storage temp. | Store below +30°C. |
| solubility | methanol: soluble1g/10 mL |
| form | Crystalline Powder |
| pka | 14.69±0.40(Predicted) |
| color | White |
| PH | 3.8-4.1 (40g/l, H2O, 20℃) |
| Water Solubility | Soluble in water(90g/L). |
| Merck | 14,2110 |
| BRN | 878191 |
| CAS DataBase Reference | 79-07-2(CAS DataBase Reference) |
| NIST Chemistry Reference | Acetamide, 2-chloro-(79-07-2) |
| EPA Substance Registry System | Acetamide, 2-chloro- (79-07-2) |
Safety information for Chloroacetamide
| Signal word | Danger |
| Pictogram(s) |
 Skull and Crossbones Acute Toxicity GHS06  Health Hazard GHS08 |
| GHS Hazard Statements |
H301:Acute toxicity,oral H317:Sensitisation, Skin |
| Precautionary Statement Codes |
P201:Obtain special instructions before use. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. |
Computed Descriptors for Chloroacetamide
| InChIKey | VXIVSQZSERGHQP-UHFFFAOYSA-N |
Chloroacetamide manufacturer
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