Chloro-N,N,N′,N′-tetramethylformamidinium hexafluorophosphate
Synonym(s):TCFH
- CAS NO.：207915-99-9
- Empirical Formula: C5H12ClF6N2P
- Molecular Weight: 280.58
- MDL number: MFCD01862891
- EINECS: 627-919-5
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-05-28 06:04:35
What is Chloro-N,N,N′,N′-tetramethylformamidinium hexafluorophosphate?
The Uses of Chloro-N,N,N′,N′-tetramethylformamidinium hexafluorophosphate
Chloro-N,N,N′,N′-tetramethylformamidinium hexafluorophosphate can be used as a reactant for the synthesis of:
- Onium salts for use in peptide coupling.
- Benzotriazole based uranium reagent, a safer replacement for coupling reagents.
It can also be used as a reagent for the synthesis of:
- Cancer cell cytotoxins.
- Bioconjugation reagents.
Properties of Chloro-N,N,N′,N′-tetramethylformamidinium hexafluorophosphate
| Melting point: | 99-104 °C |
| storage temp. | 2-8°C |
| solubility | DMSO, Methanol |
| form | Powder |
| color | White to off-white |
| BRN | 7896715 |
Safety information for Chloro-N,N,N′,N′-tetramethylformamidinium hexafluorophosphate
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for Chloro-N,N,N′,N′-tetramethylformamidinium hexafluorophosphate
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