CGS-21680 HYDROCHLORIDE
Synonym(s):2-p-(2-Carboxyethyl)phenethylamino-5′-N-ethylcarboxamidoadenosine hydrochloride hydrate;Adenosine A2A Receptor Agonist I, CGS 21680, Hydrochloride - CAS 124182-57-6 - Calbiochem;CGS-21680, CGS21680, 3-(4-(2-((6-amino-9-((2R,3R,4S,5S)-5-(ethylcarbamoyl)-3,4-dihydroxytetrahydrofuran-2-yl)-9H-purin-2-yl)amino)ethyl)phenyl)propanoic acid
- CAS NO.：124182-57-6
- Empirical Formula: C23H30ClN7O6
- Molecular Weight: 535.98
- MDL number: MFCD00078573
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-01-13 11:13:27
What is CGS-21680 HYDROCHLORIDE?
Chemical properties
White Solid
The Uses of CGS-21680 HYDROCHLORIDE
A selective A2A receptor agonist
Biological Activity
A 2A adenosine receptor agonist (K i = 27 nM). Has affinity for A 1 and A 3 adenosine receptors but can be used to distinguish A 2A - and A 2B -mediated effects.
Biochem/physiol Actions
Adenosine receptor agonist, which possesses selectivity for A2 verses A1 receptors.
Properties of CGS-21680 HYDROCHLORIDE
| storage temp. | −20°C |
| solubility | 45% (w/v) aq 2-hydroxypropyl-β-cyclodextrin: 20 mg/mL |
| form | solid |
| color | white |
| CAS DataBase Reference | 124182-57-6 |
Safety information for CGS-21680 HYDROCHLORIDE
Computed Descriptors for CGS-21680 HYDROCHLORIDE
| InChIKey | QPHVMNOEKKJYJO-MJWSIIAUSA-N |
New Products
4-Nitrobenzoic acid p-Tolualdehyde 4-Chlorobenzaldehyde 2-Fluorobenzaldehyde Diethylene glycol monomethyl ether 3-Chlorobenzaldehyde N5-(2-aminoethyl)pyridine-2,5-diamine hydrochloride N-Nitroso Desloratadine Ornidazole EP impurity C Domperidone Impurity Valsartan Desalkyl Clomiphene benzophenone analog 3,5-Dibromo-2-Nitropyridine Tert-butyl 4-(6-nitropyridine-3-yl)piperazine-1-carbaxylate 1-Methyl-4-(6-aminopyridin-3-yl)piperazine 2,5-Dichloro-4-Methylpyridine 2,4,5-Trichloropyridine 5-((4-Ethylpiperazin-1-yl)methyl)pyridin-2-amineRelated products of tetrahydrofuran
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