CGP 42112
Synonym(s):Nα-Nicotinoyl-Tyr-(Nα-Cbz-Arg)-Lys-His-Pro-Ile
- CAS NO.：127060-75-7
- Empirical Formula: C52H69N13O11
- Molecular Weight: 1052.18
- MDL number: MFCD00133611
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-04-24 14:58:28
What is CGP 42112?
Definition
ChEBI: CGP-42112A is a hexapeptide consisting of L-tyrosine, L-lysine, L-histidine, L-proline and L-isoleucine amino acid residues coupled in sequence and in which the amino group of the L-tyrosyl residue is substituted by a (pyridin-3-ylcarbonyl)nitrilo group and in which the L-lysyl side chain amino group is substituted by a {N(2)-[(benzyloxy)carbonyl]-L-arginyl}nitrilo group. It is a potent angiotensin II receptor type 2 (AT2 receptor) agonist. It has a role as an angiotensin receptor agonist, a vasodilator agent, an antineoplastic agent, an anti-inflammatory agent and a neuroprotective agent. It is an oligopeptide, a benzyl ester and a pyridinecarboxamide.
Biochem/physiol Actions
Potent AT2 angiotensin II receptor agonist.
Storage
Store at -20°C
Properties of CGP 42112
| Density | 1.39±0.1 g/cm3(Predicted) |
| storage temp. | -20°C |
| solubility | DMSO:350.0(Max Conc. mg/mL);332.64(Max Conc. mM) |
| pka | 3.72±0.22(Predicted) |
| form | solid |
| color | white |
| Water Solubility | Soluble to 1 mg/ml in water |
| BRN | 8184948 |
Safety information for CGP 42112
Computed Descriptors for CGP 42112
New Products
3-AMINO-3-(2-FLUORO-PHENYL)-PROPIONIC ACID Pentadecanoic acid Hendecanoic acid 2-AMINO-3-METHYLQUINOLINE HYDROCHLORIDE 3-Hydroxypropionitrile DL-3-Amino-3-(2-methoxyphenyl)propionic acid 2-Bromo-5-Iodopyridine 2,3-Diamino-5-Chloropyridine 2-Amino-3-Hydroxypyridine 2,6-Diamino Pyridine 4-Amino-2-Chloropyridine 2-Hydroxy-4-Picoline 4-(4-(Dimethylamino)-1-(4-fluorophenyl)-1-hydroxybutyl)-3-(hydroxymethyl)benzonitrile 2-Hydroxy-5-methoxybenzoic acid 2-Cyanopyrimidine Xanthene-9-carboxylic acid 4,4-Diethoxybutanenitrile Methyl 4-amino-2,3-difluoro-5-nitrobenzoate 5-fluoro-1,3-benzodioxole 5-Phenyl-[1,3,4]-thiadiazol-2-amine 2-Chloro-6-nitro benzothiazole 4-Chloro-2-methyl quinoline 2-Amino-4-phenyl-thiazole 2-(Chloromethyl) quinazolin-4(3H)-oneRelated products of tetrahydrofuran
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