CC-885
- CAS NO.：1010100-07-8
- Empirical Formula: C22H21ClN4O4
- Molecular Weight: 440.88
- MDL number: MFCD31657329
- Update Date: 2026-05-27 23:31:31
What is CC-885?
Description
CC-885 is a potent Cereblon Modulator with potent antitumor activity mediated through the degradation of GSPT1. was demonstrated to mediate antitumor effects through the recruitment and degradation of G1 to S phase transition 1 protein (GSPT1). GSPT1 (also named eRF3a) is a translation termination factor that binds eukaryotic translation termination factor 1 (eFR1) to mediate stop codon recognition and nascent protein release from the ribosome.
Properties of CC-885
| solubility | DMSO:40.0(Max Conc. mg/mL);90.72(Max Conc. mM) DMSO:PBS (pH 7.2) (1:4):0.2(Max Conc. mg/mL);0.45(Max Conc. mM) DMF:12.5(Max Conc. mg/mL);28.35(Max Conc. mM) |
| form | A crystalline solid |
| color | White to off-white |
Safety information for CC-885
Computed Descriptors for CC-885
New Products
6-Hydroxy-2,4-Diaminopyrimidine 2,6-Dipicolic Acid 3-AMINO-3-(2-CHLORO-PHENYL)-PROPIONIC ACID 4-Fluorophenylglycine 1-N-Boc-3-(aminoethyl)azetidine Dimedone 1-Boc-3-(cyanomethyl)azetidine N-BOC-piperidine-4-carboxylic acid 3-Hydroxypyridine 2-Bromo-5-Chloro-3-Nitropyridine 2-Amino-3-Nitro-5-Chloro Pyridine 2-Amino-5-Iodopyridine 5-Amino-2-Hydroxypyridine 2,5-Dibromopyridine 2-BROMOACETYL BROMIDE-D2 METHANE SULFONIC ACID-D4 PHOSPORIC ACID-D3 85 W% IN D2O DEUTERIUM OXIDE FOR NMR BENZENE-D6 TOLUENE-D3 5-Acetylsalicylamide 1-(3-Chlorophenyl)-4-(3-Chloropropyl) piperazine hydrochloride 4-(Methyl amino)-3-Nitro benzoic acid 3,4,5-Trimethoxy benzoic acidRelated products of tetrahydrofuran
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