carboquone

Originator

Esquinon,Sankyo,Japan,1974

Definition

ChEBI: Carboquone is an organic molecular entity.

Manufacturing Process

In 10 ml of ethanol was dissolved with heating 200 mg of 2-methyl-5-(1- methoxy-2-carbamoyloxyethyl)-1,4-benzoquinone and the resulting solution was cooled. To the cooled solution was added 0.5 ml of aziridine and then the resulting mixture was allowed to stand in a refrigerator at 5°C to 8°C for 4 days. Thereafter, the crystalline substance which precipitated in situ was recovered by filtration and washed with ethanol to give 50 mg of the desired product as red crystals melting at 200°C (with decomposition).

Therapeutic Function

Antineoplastic

Safety Profile

A poison via ingestion,intraperitoneal, subcutaneous, and intravenous routes.Mutation data reported. When heated to decomposition itemits toxic NOx.