Calanolide a
- CAS NO.：142632-32-4
- Empirical Formula: C22H26O5
- Molecular Weight: 370.44
- MDL number: MFCD00867485
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-09-12 18:48:19
What is Calanolide a?
The Uses of Calanolide a
(+)-Calanolide A is an experimental non-nucleoside reverse transcriptase inhibitor. It has potent anti-HIV activity.
Definition
ChEBI: (+)-calanolide A is an organic heterotetracyclic compound that is 11,12-dihydro-2H,6H,10H-dipyrano[2,3-f:2',3'-h]chromen-2-one substituted by a hydroxy group at position 12, methyl groups at positions 6, 6, 10 and 11 and a propyl group at position 4 (the 10R,11S,12S stereoisomer). Isolated from Calophyllum lanigerum var austrocoriaceum and Calophyllum brasiliense, it exhibits potent activity against HIV-1 reverse transcriptase. It has a role as a HIV-1 reverse transcriptase inhibitor and a plant metabolite. It is an organic heterotetracyclic compound, a delta-lactone, a cyclic ether and a secondary alcohol.
Safety information for Calanolide a
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