Cafedrine
- CAS NO.：58166-83-9
- Empirical Formula: C18H23N5O3
- Molecular Weight: 357.412
- MDL number: MFCD00865826
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-02-02 18:10:39
What is Cafedrine?
Originator
Praxinor,Merck Lipha Sante
The Uses of Cafedrine
(-)-Cafedrine is composed of linked Phenylpropanolamine (P336100) and Theophylline (T343850). It is used to regulate and restore blood pressure.
Manufacturing Process
7.5 g 7-(2-bromethyl)theophylline, 11.3 g 1-norphedrine and 12.5 ml
isopropanol were refluxed with stirring for 6 hours. Then 30 ml ethanol and
HCl in ethanol to pH 5-6 were added. The mixture stood for 2 days. 9.6 g of
7-(2-(beta-hydroxy-alpha-methylphenethylamino)ethyl)theophylline
hydrochloride was filtered off and dried. MP 243°-244°C.
In practice it is usually used as free base.
Therapeutic Function
Analeptic
Properties of Cafedrine
| Boiling point: | 591.6±52.0 °C(Predicted) |
| Density | 1.33±0.1 g/cm3(Predicted) |
| pka | 13.90±0.20(Predicted) |
Safety information for Cafedrine
Computed Descriptors for Cafedrine
New Products
N,N CARBONYL DIIMIDAZOLE 2-Amino-5-bromo-4-(trifluoromethyl)pyridine（RM for Indian lab) (RS)-beta-Amino-beta-(4-bromophenyl)propionic acid Tetrabutylammonium perchlorate N,O-Dimethylhydroxylamine hydrochloride (R)-1-Benzyl-3-pyrrolidinecarbonitrile Bupropian related compound F Lantanoprost rc B Clidinium Bromide Impurity Noradrenaline EP Impurity D/Noradrenaline Methyl Ether Cetirizine EP Impurity A/Cetirizine CBHP Impurity N-Nitroso hydroxy Cetrizine EP Impurity-A 4-(5-amino-1-methyl-1h-benzoimidazol-2-yl)-butyric acid isopropyl ester. 1,4-bis(methylsulfonyl)butane 4-Cyano-N-Methacryloyl-3-Trifluoromethyl Aniline 5-Methyl-1,3-benzenediacetonitrile 4-Fluorothiophenol 1-methyl amino-2,4-dinitro benzene 2-Chloro Benzylcyanide 3,4 Diethoxy Benzylcyanide 3,4 Dimethoxy Benzylcyanide 3-chlorobenzyl cyanide 3-Hydroxypropionitrile 4-Bromo BenzylcyanideRelated products of tetrahydrofuran
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