Cafedrine
- CAS NO.：58166-83-9
- Empirical Formula: C18H23N5O3
- Molecular Weight: 357.412
- MDL number: MFCD00865826
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-05-11 16:31:51
What is Cafedrine?
Originator
Praxinor,Merck Lipha Sante
The Uses of Cafedrine
(-)-Cafedrine is composed of linked Phenylpropanolamine (P336100) and Theophylline (T343850). It is used to regulate and restore blood pressure.
Manufacturing Process
7.5 g 7-(2-bromethyl)theophylline, 11.3 g 1-norphedrine and 12.5 ml
isopropanol were refluxed with stirring for 6 hours. Then 30 ml ethanol and
HCl in ethanol to pH 5-6 were added. The mixture stood for 2 days. 9.6 g of
7-(2-(beta-hydroxy-alpha-methylphenethylamino)ethyl)theophylline
hydrochloride was filtered off and dried. MP 243°-244°C.
In practice it is usually used as free base.
Therapeutic Function
Analeptic
Properties of Cafedrine
| Boiling point: | 591.6±52.0 °C(Predicted) |
| Density | 1.33±0.1 g/cm3(Predicted) |
| pka | 13.90±0.20(Predicted) |
Safety information for Cafedrine
Computed Descriptors for Cafedrine
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