C16 ceramide
Synonym(s):N-palmitoyl-D-erythro-sphingosine;C16-Ceramide;Cer(d18:1/16:0);C16 Ceramide (d18:1/16:0);(2S,3R,4E)-2-(Palmitoylamino)-4-octadecene-1,3-diol
- CAS NO.：24696-26-2
- Empirical Formula: C34H67NO3
- Molecular Weight: 537.9
- MDL number: MFCD00056205
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-09-12 18:49:13
What is C16 ceramide?
Chemical properties
White Crystalline Solid
The Uses of C16 ceramide
A predominant, rather hydrophobic natural ceramide. Activates a cytosolic serine/threonine protein phosphatase in T9 cells; induces EGF receptor phosphorylation in A-431 cells; stimulates ceramide-activated protein kinase
The Uses of C16 ceramide
An endogenous ceramide that acts as a lipid second messenger to regulate apoptosis and stress signaling.
What are the applications of Application
C16 Ceramide (N-Palmitoylsphingosine, D-erythro) is an endogenous ceramide
Definition
ChEBI: N-hexadecanoylsphingosine is a N-acylsphingosine in which the ceramide N-acyl group is specified as hexadecanoyl (palmitoyl). It has a role as a Mycoplasma genitalium metabolite and a human blood serum metabolite. It is a N-acylsphingosine, a Cer(d34:1) and a N-palmitoyl-sphingoid base. It is functionally related to a hexadecanoic acid.
Properties of C16 ceramide
| Melting point: | 94-95 °C |
| Boiling point: | 614.41°C (rough estimate) |
| Density | 0.9596 (rough estimate) |
| refractive index | 1.6630 (estimate) |
| storage temp. | −20°C |
| solubility | Soluble in DMF at 0.15mg/ml |
| form | Crystalline Powder |
| pka | 13.54±0.20(Predicted) |
| color | White |
| CAS DataBase Reference | 24696-26-2 |
Safety information for C16 ceramide
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P304+P340:IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P405:Store locked up. |
Computed Descriptors for C16 ceramide
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