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HomeProduct name listButenafine hydrochloride

Butenafine hydrochloride

Synonym(s):Butenafine hydrochloride;Mentax;N-(p-tert-butylbenzyl)-N-methyl-1-naphthalenemethylamine hydrochloride;N-[[4-(1,1-Dimethylethyl)phenyl]methyl]-N-methyl-1-naphthalenemethanamine hydrochloride

  • CAS NO.:101827-46-7
  • Empirical Formula: C23H27N.ClH
  • Molecular Weight: 353.93
  • MDL number: MFCD00917064
  • EINECS: 642-354-4
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2023-09-15 17:55:00
Butenafine hydrochloride Structural

What is Butenafine hydrochloride?

Description

Butenafine hydrochloride is a new benzylamine antifungal which appears to block the squalene epoxidation step of sterol synthesis in fungi. Active against a broad spectrum of fungi, butenafine hydrochloride is more effective in a guinea-pig model of tinea pedis than clotrimazole, naftifine and tolnaftate. Its efficacy is partially attributed to its long retention time in the skin.

The Uses of Butenafine hydrochloride

Butenafine hydrochloride has been used as a standard in high-performance liquid chromatography (HPLC) method to determine butenafine hydrochloride in butenafine-loaded nanosponges.

What are the applications of Application

Butenafine Hydrochloride is a compound with antifungal properties

Properties of Butenafine hydrochloride

Melting point: 210-214°C
storage temp.  room temp
solubility  DMSO: ≥10mg/mL
form  powder
color  white to off-white

Safety information for Butenafine hydrochloride

Signal word Warning
Pictogram(s)

Exclamation Mark
Irritant
GHS07
GHS Hazard Statements H312:Acute toxicity,dermal
Precautionary Statement Codes P280:Wear protective gloves/protective clothing/eye protection/face protection.

Computed Descriptors for Butenafine hydrochloride

InChIKey LJBSAUIFGPSHCN-UHFFFAOYSA-N

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