BPV(PHEN)
Synonym(s):bpV(phen) - CAS 42494-73-5 - Calbiochem;Potassium bisperoxo(1,10-phenanthroline)oxovanadate (V) hydrate;Potassium Bisperoxo(1,10-phenanthroline)oxovanadate (V), PTEN Inhibitor I, PTP Inhibitor VIII
- CAS NO.：42494-73-5
- Empirical Formula: C12H8N2O5V.K
- Molecular Weight: 350.24
- MDL number: MFCD32671691
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-05-28 05:18:16
What is BPV(PHEN)?
General Description
The water content varies from lot to lot and is supplied on the label along with the lot-specific molecular weight.
Biochem/physiol Actions
bpV(phen) is an insulin receptor kinase (IRK) activator and an inhibitor of protein phosphotyrosine phosphatases with selectivity for PTEN, phosphatase and tensin homolog, a tumour suppressor phosphatase involved in cell cycle regulation. IC50 values for bpV(phen) are 38 nM for PTEN compared to 343 nM for PTPβ and 920 nM for PTP-1β. bpV(phen) has anti-inflammatory effects in oxidative stress including inhibitory effects on oxidative stress-induced cardiomyocyte injury that may be partially modulated by the action of ROS on PTEN. It may also be involved in differentiation.
Properties of BPV(PHEN)
| storage temp. | -20°C |
| solubility | H2O: soluble20mg/mL, clear |
| form | Yellow solid |
| color | faint yellow to dark yellow |
Safety information for BPV(PHEN)
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for BPV(PHEN)
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