BPV(HOPIC)

Synonym(s):Bisperoxovanadium(HOpic);Dipotassium bisperoxo (5-hydroxypyridine-2-carboxyl) oxovanadate (V);K₂[VO(O₂)2C₆H₄NO₃]

CAS NO.：722494-26-0
Empirical Formula: C6H4K2NO8V
Molecular Weight: 347.24
MDL number: MFCD01862576
SAFETY DATA SHEET (SDS)
Update Date: 2026-07-27 17:00:41

What is BPV(HOPIC)?

The Uses of BPV(HOPIC)

bpV(HOpic) has been used in pharmacological perturbation of cell migration related signaling pathway.

What are the applications of Application

bpV(HOpic) is a protein PTP inhibitor

Biochem/physiol Actions

bpV(OHpic) is a bisperoxovanadium inhibitor of protein phosphotyrosine phosphatases with selectivity for PTEN, phosphatase and tensin homolog, a tumour suppressor phosphatase involved in cell cycle regulation. IC50 values for bpV(HOpic) are 14 nM for PTEN compared to 4.9 μM for PTPβ and 25.3 μM for PTP-1β. bpV(HOpic) has been shown to enhance PI3K/Akt signaling that could prevent myocardium from ischemia-reperfusion injury.

Properties of BPV(HOPIC)

storage temp.	-20°C
solubility	H2O: soluble20mg/mL, clear
form	powder
color	faint yellow to dark yellow

Safety information for BPV(HOPIC)

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation
Precautionary Statement Codes	P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P332+P313:IF SKIN irritation occurs: Get medical advice/attention. P337+P313:IF eye irritation persists: Get medical advice/attention.

Computed Descriptors for BPV(HOPIC)

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