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HomeProduct name listBOC-8-AMINOCAPRYLIC ACID

BOC-8-AMINOCAPRYLIC ACID

Synonym(s):8-(Boc-amino)caprylic acid;8-(Boc-amino)octanoic acid

BOC-8-AMINOCAPRYLIC ACID Structural

What is BOC-8-AMINOCAPRYLIC ACID?

Description

Boc-8-aoc-oh can be used as a PROTAC linker in the synthesis of PROTACs. Boc-8-aoc-oh is an alkane chain with terminal carboxlic acid and Boc-protected amino groups. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. The Boc group can be deprotected under mild acidic conditions to form the free amine.

Chemical properties

White amorphous powder

The Uses of BOC-8-AMINOCAPRYLIC ACID

Reagent to introduce a protected w-amino alkyl spacer. Longer spacer arms often impart increased activity to the substrate

Properties of BOC-8-AMINOCAPRYLIC ACID

Melting point: 56-59 °C
Boiling point: 406.0±28.0 °C(Predicted)
Density  1.036±0.06 g/cm3(Predicted)
storage temp.  Keep in dark place,Sealed in dry,Room Temperature
pka 4.78±0.10(Predicted)
BRN  2268966

Safety information for BOC-8-AMINOCAPRYLIC ACID

Computed Descriptors for BOC-8-AMINOCAPRYLIC ACID

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