BOC-7-AMINO-HEPTANOIC ACID
Synonym(s):7-(Boc-amino)enanthic acid;7-(Boc-amino)heptanoic acid;Boc-7-aminoheptanoic acid
- CAS NO.：60142-89-4
- Empirical Formula: C12H23NO4
- Molecular Weight: 245.32
- MDL number: MFCD00063356
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-04-22 18:57:36
What is BOC-7-AMINO-HEPTANOIC ACID?
Description
Boc-7-Aminoheptanoic acid can be used as a PROTAC linker in the synthesis of PROTACs and other conjugation applicaitons. Boc-7-Aminoheptanoic acid is an alkane chain with terminal carboxlic acid and Boc-protected amino groups. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. The Boc group can be deprotected under mild acidic conditions to form the free amine.
Properties of BOC-7-AMINO-HEPTANOIC ACID
| Melting point: | 56-60 °C |
| Boiling point: | 393.1±25.0 °C(Predicted) |
| Density | 1.050±0.06 g/cm3(Predicted) |
| storage temp. | 2-8°C |
| solubility | soluble in Methanol |
| form | powder to crystaline |
| pka | 4.77±0.10(Predicted) |
| color | White to Almost white |
| BRN | 2050867 |
| CAS DataBase Reference | 60142-89-4(CAS DataBase Reference) |
Safety information for BOC-7-AMINO-HEPTANOIC ACID
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H302:Acute toxicity,oral H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for BOC-7-AMINO-HEPTANOIC ACID
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