Boc-1-amino-3,6-dioxa-8-octanediamine
Synonym(s):N-Boc-3,6-dioxa-1,8-octanediamine;tert-Butyl 2-[2-(2-aminoethoxy)ethoxy]ethylcarbamate
- CAS NO.:153086-78-3
- Empirical Formula: C11H24N2O4
- Molecular Weight: 248.32
- MDL number: MFCD03788155
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-07-16 07:06:08
What is Boc-1-amino-3,6-dioxa-8-octanediamine?
Description
t-Boc-N-Amido-PEG2-amine is a PEG linker containing an amino group and Boc-protected amino group. The hydrophilic PEG spacer increases solubility in aqueous media. The amino group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The Boc group can be deprotected under mild acidic conditions to form the free amine.
Chemical properties
Light yellow oil
The Uses of Boc-1-amino-3,6-dioxa-8-octanediamine
Linker reagent for the prep. of a broad variety of linked tags, monomers for polymerisation, ionophores etc., e.g. biotinylation reagents.
What are the applications of Application
N-Boc- 2,2′-(ethylenedioxy)diethylamine is a linker reagent for the prep. of a broad variety of linked tags, monomers for polymerization, ionophores etc., e.g. biotinylation reagents
Properties of Boc-1-amino-3,6-dioxa-8-octanediamine
| Boiling point: | 365.2±27.0 °C(Predicted) |
| Density | 1.046 g/mL at 20 °C |
| refractive index | 1.4570 to 1.4610 |
| storage temp. | under inert gas (nitrogen or Argon) at 2–8 °C |
| form | clear liquid |
| pka | 12.23±0.46(Predicted) |
| color | Colorless to Light yellow to Light orange |
| InChI | InChI=1S/C11H24N2O4/c1-11(2,3)17-10(14)13-5-7-16-9-8-15-6-4-12/h4-9,12H2,1-3H3,(H,13,14) |
Safety information for Boc-1-amino-3,6-dioxa-8-octanediamine
| Signal word | Warning |
| Pictogram(s) |
![]() Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H302:Acute toxicity,oral H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for Boc-1-amino-3,6-dioxa-8-octanediamine
| InChIKey | OCUICOFGFQENAS-UHFFFAOYSA-N |
| SMILES | C(OC(C)(C)C)(=O)NCCOCCOCCN |
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![2-[2-[2-[2-(BENZYLOXY)ETHOXY]ETHOXY]ETHOXY]ETHANOL](https://img.chemicalbook.in/CAS/GIF/86259-87-2.gif)






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