Nonaethylene Glycol Monomethyl Ether
- CAS NO.：6048-68-6
- Empirical Formula: C19H40O10
- Molecular Weight: 428.51
- MDL number: MFCD06797148
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-04-21 10:31:43
What is Nonaethylene Glycol Monomethyl Ether ?
Description
m-PEG9-alcohol is a PEG linker containing a hydroxyl group. The hydroxyl group enables further derivatization or replacement with other reactive functional groups. The hydrophilic PEG spacer increases solubility in aqueous media.
Definition
ChEBI: Nonaethylene glycol monomethyl ether is nonaethylene glycol in which one of the hydroxy groups is substituted by methoxy. It is functionally related to a nonaethylene glycol.
in vitro
Nonaethylene glycol monomethyl ether is a PEG-based PROTAC linker that can be used to synthesize PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase, and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
Properties of Nonaethylene Glycol Monomethyl Ether
| Melting point: | 14 °C |
| Boiling point: | 170 °C(Press: 0.01 Torr) |
| Density | 1.10 |
| refractive index | 1.4570 to 1.4620 |
| pka | 14.36±0.10(Predicted) |
| form | clear liquid |
| color | Colorless to Light yellow to Light orange |
| InChI | InChI=1S/C19H40O10/c1-21-4-5-23-8-9-25-12-13-27-16-17-29-19-18-28-15-14-26-11-10-24-7-6-22-3-2-20/h20H,2-19H2,1H3 |
Safety information for Nonaethylene Glycol Monomethyl Ether
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H302:Acute toxicity,oral H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P280:Wear protective gloves/protective clothing/eye protection/face protection. P301+P312:IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for Nonaethylene Glycol Monomethyl Ether
| InChIKey | VVHAVLIDQNWEKF-UHFFFAOYSA-N |
| SMILES | C(O)COCCOCCOCCOCCOCCOCCOCCOCCOC |
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