bisoxatin

Absorption

Once dissociated from acetate, some bisoxatin is absorbed with a Tmax of 4 h .

The Uses of bisoxatin

Laxative.

Indications

For use in the treatment of constipation in the absence of bowel obstruction and for surgical preparation of the colon .

Background

Bisoxatin is a stimulant laxative which increases peristalsis and inhibits absorbtion of water and ions in the intestine . It is marketed in Belgium under the tradename Wylaxine and used for the treatment of constipation and for preparation of the colon for surgical procedures.

Definition

ChEBI: Bisoxatin is a diarylmethane.

Pharmacokinetics

Bisoxatin is a stimulant laxative which increases peristalsis and inhibits the absorbtion of water and ions in the intestine . This increases the water content of the feces and increases its movement through the intestine.

Metabolism

Absorbed compound is metabolized to bisoxatin glucuronide .