bis(3',5')-cyclic diguanylic acid

CAS NO.：61093-23-0
Empirical Formula: C20H24N10O14P2
Molecular Weight: 690.41
MDL number: MFCD31563661
SAFETY DATA SHEET (SDS)
Update Date: 2026-06-12 16:21:36

What is bis(3',5')-cyclic diguanylic acid?

The Uses of bis(3',5')-cyclic diguanylic acid

Cyclic-di-GMP sodium salt has been used as a quorum sensing molecule.

Definition

ChEBI: A cyclic purine dinucleotide that is the 3',5'-cyclic dimer of MP.

Biochem/physiol Actions

Cyclic-di-GMP is a naturally occurring small molecule that acts as a bacterial second messenger to regulate important signaling mechanisms in prokaryotes that control bacterial survival, adhesion, colonization, biofilm formation, and virulence factors production. During infections Cyclic-di-GMP is bound by host STING (stimulator of interferon genes) leading to expression of interferon genes, activating innate immune responses. c-di-GMP has been found in eukarotic systems acting not only in immune response, but as an inhibitor of the pacemaker I(f) current in the heart.

Properties of bis(3',5')-cyclic diguanylic acid

Melting point:	193-196 °C (decomp)
Density	2.70±0.1 g/cm3(Predicted)
storage temp.	-20°C
form	powder
pka	0.66±0.70(Predicted)
color	white to beige
Water Solubility	Soluble in Water

Safety information for bis(3',5')-cyclic diguanylic acid

Computed Descriptors for bis(3',5')-cyclic diguanylic acid

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