BIOTIN-NHS
Synonym(s):Biotin-NHS;NHS-Biotin;Biotin-OSu;BNHS;N-(Biotinyloxy)succinimide
- CAS NO.：35013-72-0
- Empirical Formula: C14H19N3O5S
- Molecular Weight: 341.38
- MDL number: MFCD00078531
- EINECS: 609-055-0
- SAFETY DATA SHEET (SDS)
- Update Date: 2025-12-05 14:33:18
What is BIOTIN-NHS?
Description
N-
Chemical properties
White Solid
The Uses of BIOTIN-NHS
Biotin-NHS is used in the biotinylation of proteins and peptides. Couples with primary amine in the pH range 6.5-8.5.
The Uses of BIOTIN-NHS
Amino reactive biotin reagent for preparing biotinylated surfaces or polypeptides.
The Uses of BIOTIN-NHS
amine reactive biotinylation reagent
Purification Methods
Recrystallise the ester from refluxing isoPrOH and dry it in a vacuum over P2O5 + KOH. [Jasiewicz et al. Exp Cell Biol 100 213 1976.]
Properties of BIOTIN-NHS
| Melting point: | 212-214 °C |
| Density | 1.45±0.1 g/cm3(Predicted) |
| storage temp. | -20°C |
| solubility | DMF: ≤50 mg/mL Stable for at least one month in dry DMF |
| form | powder |
| pka | 13.89±0.40(Predicted) |
| color | White to off-white |
| BRN | 4720781 |
| Stability: | Stable. Incompatible with strong oxidizing agents. |
| CAS DataBase Reference | 35013-72-0(CAS DataBase Reference) |
Safety information for BIOTIN-NHS
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection. |
Computed Descriptors for BIOTIN-NHS
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