Bicalutamide-d4
- CAS NO.：1185035-71-5
- Empirical Formula: C18H10D4F4N2O4S
- Molecular Weight: 434.4
- MDL number: MFCD08063408
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-09-12 18:51:26
What is Bicalutamide-d4?
Description
Bicalutamide-d4 is intended for use as an internal standard for the quantification of bicalutamide by GC- or LC-MS. Bicalutamide is a non-steroidal androgen receptor antagonist that binds the androgen receptor (Ki = 12.5 μM; IC50 = 1.2 μM), preventing its activation and subsequent upregulation of androgen responsive genes by androgenic hormones. Bicalutamide is frequently used to examine the role of androgen receptor inactivation in the proliferation of prostate cancer cells and has served as a molecular template for the design and structural optimization of more selective androgen receptor modulators for androgen therapy.
Chemical properties
BICALUTAMIDE-D4 is White Solid
The Uses of Bicalutamide-d4
BICALUTAMIDE-D4 is used as an antiandrogen, antineoplastic (hormonal). (94%d4; 5.7%d3, 0.1%d1, no d0
What are the applications of Application
Bicalutamide-d4 is an androgen antagonist and antineoplastic
Properties of Bicalutamide-d4
| Melting point: | 192-1940C |
| storage temp. | -20°C Freezer |
| solubility | Chloroform (Slightly, Heated), Methanol (Slightly, Sonicated) |
| form | Solid |
| color | White to Off-White |
Safety information for Bicalutamide-d4
Computed Descriptors for Bicalutamide-d4
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