Azidoacetic acid methyl ester
- CAS NO.：1816-92-8
- Empirical Formula: C3H5N3O2
- Molecular Weight: 115.0907
- MDL number: MFCD01311034
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-05-28 03:35:43
What is Azidoacetic acid methyl ester?
The Uses of Azidoacetic acid methyl ester
- Methyl 2-azidoacetate is widely used as a precursor to build triazole derivatives via alkyne-azide click chemistry. Some of the examples include the synthesis of coumarin-triazole derivatives as potential antiplasmodial agents and macrocyclic triazole containing largazole analogs as histone deacetylases-1 (HDAC1) inhibitors.
- It can be used to synthesize various pyrrole derivatives by Knoevenagel condensation as in the synthesis of near-infrared boron dipyrromethene (BODIPY) donors for organic tandem solar cells.
- It can also be used in Hemetsberger-Knittel synthesis of substituted 5-, 6-, and 7-azaindoles.
- Synthesis of highly fluorescent pyreno[2,1-b]pyrroles using methyl 2-azidoacetate as one of the reagents.
Properties of Azidoacetic acid methyl ester
| Boiling point: | 35 °C |
| Density | 1.182 g/mL at 25 °C |
| refractive index | n20/D1.440 |
| Flash point: | 48℃ |
Safety information for Azidoacetic acid methyl ester
| Signal word | Warning |
| Pictogram(s) |
 Flame Flammables GHS02  Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H226:Flammable liquids H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for Azidoacetic acid methyl ester
Azidoacetic acid methyl ester manufacturer
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product: Methyl 2-Azidoacetate 1816-92-8 99%
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