Azide-PEG3-Desthiobiotin
- CAS NO.：1426828-06-9
- Empirical Formula: C18H34N6O5
- Molecular Weight: 414.51
- Update Date: 2025-07-16 09:55:32
What is Azide-PEG3-Desthiobiotin?
Description
Desthiobiotin is a single-ring, sulfur-free analog of biotin that binds to streptavidin with nearly equal specificity but less affinity than biotin (Kd?= 1011?vs. 1015M, respectively). Consequently, desthiobiotinylated proteins can be eluted readily and specifically from streptavidin affinity resin using mild conditions based on competitive displacement with free biotin. For pull-down experiments with biological samples, this soft-release characteristic of desthiobiotin also helps to minimize co-purification of endogenous biotinylated molecules, which remain bound to streptavidin upon elution of the target protein complexes with free biotin.
What are the applications of Application
Desthiobiotin-PEG3-azide is Desthiobiotin-PEG3-azide is an azide PEG-linker
Properties of Azide-PEG3-Desthiobiotin
| form | clear liquid |
| color | Colorless to Yellow to Orange |
Safety information for Azide-PEG3-Desthiobiotin
Computed Descriptors for Azide-PEG3-Desthiobiotin
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